---
title: When you live in times when every platelet concentrate counts
description: Applying pathogen inactivation technologies to platelet concentrates can extend their shelf life from 5 to 7 days.
image: https://insights.interceptbloodsystem.com/hubfs/multiple_platelets_2.jpg
---

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# When you live in times when every platelet concentrate counts

22/04/2020

- [Cerus](https://insights.interceptbloodsystem.com/topic/cerus)

**![multiple_platelets_2](https://insights.interceptbloodsystem.com/hs-fs/hubfs/multiple_platelets_2.jpg?width=400&name=multiple_platelets_2.jpg)**With the outbreak of COVID-19 maintaining adequate inventory levels for platelet concentrates may be even more challenging than ever.

Applying pathogen inactivation technologies to platelet concentrates can extend their **shelf life from 5 to 7 days\***, but there have been few systematic studies of the repercussions of such technologies on **outdate rates, clinical efficacy and safety**.

**Outdating rates**  
Findings from recent published Spanish studies1 indicate that if a reasonable production policy is followed then a **shift from 5 to 7 days enables outdates to be almost entirely eliminated** (the reductions obtained range from 88% to 100%).

Also, a **subsequent reduction in outdating at hospitals are to be expected** as platelet concentrates arrive at hospitals with almost two more days of remaining life time.

**Clinical efficacy and safety**  
The University Hospital Basel recently published results of a large retrospective two-cohort study2 which looked at clinical efficacy and safety of INTERCEPTTM treated **platelet concentrates stored for up to 7 days**.

Transfusion of pathogen inactivated platelet concentrates more than 5 days old compared with 5 days old or less **did not increase platelet concentrates and RBC use** on the same or next day as an indirect measure of hemostasis and did not increase transfusion reactions.

**Mean number of platelet concentrates used per patient and duration of support were not different** for hematology/oncology, allogeneic and autologous hematopoietic stem cell transplant, and general medical/surgical patients.

**Routine use**  
INTERCEPTTM Blood System treated platelet concentrates stored for more than 5 days have been transfused in **Sweden, Spain, Belgium, Iceland, Portugal, and Switzerland**. In April 2018, the **French health authority**, Agence Nationale de Sécurité du Médicament et des Produits de Santé, **approved shelf life extension to 7 days**.

Interested to find out more?  
[![Clinical efficacy and safety](https://no-cache.hubspot.com/cta/default/2866022/13ac3ef1-a956-4aea-9b4b-50407daa2e55.png)](https://cta-redirect.hubspot.com/cta/redirect/2866022/13ac3ef1-a956-4aea-9b4b-50407daa2e55)

[![Reduced outdating rates](https://no-cache.hubspot.com/cta/default/2866022/c3599737-d287-4f05-acef-97a9edbd01fc.png)](https://cta-redirect.hubspot.com/cta/redirect/2866022/c3599737-d287-4f05-acef-97a9edbd01fc)

\*The extension of platelet storage time might be subject to local regulations and may not be available in your country.

Reference:   
1Carlos Gorria et all, Impact of implementing pathogen reduction technologies for platelets on reducing outdates, Vox Sanguinis  
(2019), DOI: 10.1111/vox.12860  
2Laura Infanti et all; Clinical impact of amotosalen-ultraviolet A pathogen-inactivated platelets stored for up to 7 days; TRANSFUSION 2019;9999;1–12

[← Pathogen inactivation of blood components during outbreaks of infectious diseases in the European Union](https://insights.interceptbloodsystem.com/pathogen-inactivation-of-blood-components-during-outbreaks-of-infectious-diseases-in-the-european-union)

[Inactivation efficacy of INTERCEPT for a broad spectrum of viruses and parasites →](https://insights.interceptbloodsystem.com/inactivation-efficacy-of-intercept-for-a-broad-spectrum-of-viruses-and-parasites)

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